Publications
PART 2 - 2022
Update of recommendations for the management of COVID-19 in patients with haematological malignancies, haematopoietic cell transplantation and CAR T therapy
Simone Cesaro, Malgorzata Mikulska, Hans H. Hirsch, Jan Styczynski, Sylvain Meylan, Catherine Cordonnier, Davide Navarro, Marie von Lilienfeld-Toal, Varun Mehra, Francesco Marchesi, Caroline Besson, Raul Cordoba Masculano, Gernot Beutel, Herman Einsele, Johan Maertens, Rafael de la Camara, Per Ljungman and Livio Pagano
PART 1 - 2021
Recommendations for the management of COVID-19 in patients with haematological malignancies or haematopoietic cell transplantation, from the 2021 European Conference on Infections in Leukaemia (ECIL 9)
Simone Cesaro, Per Ljungman, Malgorzata Mikulska, Hans H. Hirsch, Marie von Lilienfeld-Toal, Catherine Cordonnier, Sylvain Meylan, Varun Mehra, Jan Styczynski, Francesco Marchesi, Caroline Besson, Fausto Baldanti, Raul Cordoba Masculano, Gernot Beutel, Herman Einsele, Elie Azoulay, Johan Maertens, Rafael de la Camara and Livio Pagano
Infectious complications of targeted drugs and biotherapies inInfectious complications of targeted drugs and biotherapies inacute leukemia. Clinical practice guidelines by the EuropeanConference on Infections in Leukemia (ECIL 9)
Georg Maschmeyer, Lars Bullinger, Carolina Garcia-Vidal, Raoul Herbrecht, Johan Maertens, Pierantonio Menna, Livio Pagano, Anne Thiebaut-Bertrand and Thierry Calandra
The first European Conference on infections in leukaemia: Why and how?
C. Cordonnier, T Calandra.
Eur J Cancer 2007; Suppl. 5, 2-4.
Quinolone prophylaxis for bacterial infections in afebrile high risk neutropenic patients
G Bucaneve, E Castagnola, C Viscoli, L Leibovici, F Menichetti
Eur J Cancer 2007; Suppl. 5, 5-12.
The need for aminoglycosides in combination with betalactams for high-risk, febrile neutropaenic patients with leukaemia
L Drgona, M Paul, G Bucaneve, T Calandra, F Menichetti
Eur J Cancer 2007; Suppl. 5. 13-22
Empirical use of anti-Gram-positive antibiotics in febrile
neutropaenic cancer patients with acute leukaemia 5
Alain Cometta*, O. Marchetti, T. Calandra
Eur J Cancer 2007; Suppl. 5. 23-31
Primary antifungal prophylaxis in leukaemia patients.
J Maertens, P Frere, C Lass-Flörl, W Heinz, OA Cornely.
Eur J Cancer 2007;Suppl.5:43-8.
Empirical antifungal therapy in neutropenic cancer patients with persistent fever. Guidelines of the ECIL1 conference.
O Marchetti, C Cordonnier, T Calandra.
Eur J Cancer 2007; Suppl. 5. 32-42.
European guidelines for the treatment of invasive candida and invasive aspergillus infections in adult haematological patients.
R Herbrecht, U Fluckiger, B Gachot, P Ribaud, A Thiebaut, C Cordonnier.
Eur J Cancer 2007; Suppl. 5., 49-59.
Management of CMV, HHV6, HHV7 and Kaposi-sarcoma herpesvirus infections in patients with hematological malignancies including stem cell transplantation.
P Ljungman, R De La Camara, C Cordonnier, H Einsele, D Engelhard, P Reusser, J Styczynski, K Ward for the European Conference on Infections in Leukemia.
Bone Marrow Transplantation, 2008, Aug;42(4):227-40).
Management of HSV, VZV, and EBV infections in patients with hematological malignancies and after SCT : guidelines from the Second European Conference on Infections in Leukemia.
J Styczynski, P Reusser, H Einsele, R de la Camara, C Cordonnier, KN Ward, P Ljungman, D Engelhard, for the European Conference on Infections in Leukemia.
Bone Marrow Transplant 2009; 43:757-770
European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: Summary of the ECIL3 – 2009 Update
J Maertens, O Marchetti, R Herbrecht, O A. Cornely, U Flückiger, P Frêre, B Gachot, W J. Heinz, C Lass-Flörl, P Ribaud, A Thiebaut, C Cordonnier
Bone Marrow Transplant, 2011 May;46(5):709-18. Download
download
The use of mannan antigen and anti-mannan antibodies in the diagnosis of invasive candidiasis:
recommendations from the 3rd European Conference on Infections in Leukemia (ECIL-3).
Authors:
M. Mikulska, T. Calandra, M. Sanguinetti, D. Poulain and C. Viscoli, on behalf of the third European Conference on Infections in Leukemia
Critical Care 2010;14(6):R222. Epub 2010 Dec 8. Download
download
Recommendations for the use of biological markers for the diagnosis of invasive fungal diseases in leukemic patients and hematopoietic stem cell transplant recipients
O Marchetti, F Lamoth, M Mikulska, C Viscoli, P Verweij, S Bretagne, and the European Conference on Infections in Leukaemia (ECIL) laboratory working groups
Bone Marrow Transplant, Epub 2011, Sept. 19.
Classical diagnostic procedures for the diagnosis of Invasive Fungal Diseases in patients with Leukemia
M Cavling Arendrup, Chris Kibbler, E Dannaoui, M Ruhnke, CP Heussel, J Bille
Bone Marrow Transplant, Epub 2012, Jan. 9.
Beta-Glucan antigenemia for the diagnosis of invasive fungal infections in patients with hematological malignancies: Systematic review and meta-analysis of cohort studies
F Lamoth, M Cruciani, C Mengoli, E Castagnola, O Lortholary, M Richardson, O Marchetti, on behalf of the Third European Conference on Infections in Leukemia (ECIL 3)
Clin Infect Dis 2012:54,633-43. Download
download
ECIL-3 classical diagnostic procedures for the diagnosis of invasive fungal diseases in patients with leukaemia MC Arendrup, J Bille, E Dannaoui, M Ruhnke, C-P Heussel, C Kibbler
Bone Marrow Transplant 2012 : 47, 1030–1045
Download
download
Diagnosis and treatment of mucormycosis in patients with haematological malignancies: guidelines from the 3rd European Conference on Infections in Leukemia (ECIL 3)
Anna Skiada, Fanny Lanternier, Andreas H. Groll, Livio Pagano, Stephan Zimmerli, Raoul Herbrecht, Olivier Lortholary, and George L. Petrikkos
Haematologica 2012 [Epub ahead of print]
European Conference on Infections in Leukemia. European guidelines for diagnosis and treatment of adenovirus infection in leukemia and stem cell transplantation: summary of ECIL-4 (2011).
S. Matthes-Martin, T. Feuchtinger, P.J. Shaw, D. Engelhard, H.H. Hirsch, C. Cordonnier, P. Ljungman, on behalf of the fourth European Conference on Infections in Leukemia (ECIL).
Transpl Infect Dis 2012: 14: 555–563.
Fourth European Conference on Infections in Leukaemia (ECIL-4): Guidelines for Diagnosis and Treatment of Human Respiratory Syncytial Virus, Parainfluenza Virus, Metapneumovirus, Rhinovirus, and Coronavirus.
Hans H. Hirsch, Rodrigo Martino, Katherine N. Ward, Michael Boeckh, Hermann Einsele, and Per Ljungman
Clinical Infectious Diseases Advance Access published November 1, 2012.
European guidelines for prevention and management of influenza in hematopoietic stem cell transplantation and leukaemia patients: summary of ECIL-4 (2011).
D. Engelhard, B. Mohty, R. de la Camara, C. Cordonnier, P. Ljungman., on behalf of ECIL, a joint venture of EBMT, EORTC, ICHS and ELN.
Transpl Infect Dis 2013: 0: 1–14
The role of antibiotic stewardship in limiting antibacterial resistance among hematology patients.
Gyssens IC, Kern WV, Livermore D, on behalf of ECIL-4, a joint venture of EBMT, EORTC, ICHS and ESGICH of ESCMID,
Haematologica 2013, 98 (12), 1821-5
European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European Conference on Infections in Leukemia.
D Averbuch, C Orasch, C Cordonnier, D M. Livermore, M Mikulska, C Viscoli, I C. Gyssens, W Kern, G Klyasova, O Marchetti, D Engelhard, M Akova, on behalf of ECIL4, a joint venture of EBMT, EORTC, ICHS, ESGICH/ESCMID and ELN.
Haematologica 2013: 98 (12): 1826-35
Targeted therapy against multi-resistant bacteria in leukemic and hematopoietic stem cell transplant recipients - guidelines of the 4th European Conference on Infections in Leukemia.
D Averbuch, C Cordonnier, D M. Livermore, M Mikulska, C Orasch, C Viscoli, I C. Gyssens, W Kern, G Klyasova, O Marchetti, D Engelhard, M Akova, on behalf of ECIL4, a joint venture of EBMT, EORTC, ICHS, ESGICH/ESCMID and ELN.
Haematologica 2013: 98 (12): 1836-47
Aetiology and resistance in bacteraemias among adult and paediatric haematology and cancer patients.
Mikulska M, Viscoli C, Orasch C, Livermore DM, Averbuch D, Cordonnier C, Akova M, for the Fourth European Conference on Infections in Leukemia Group (ECIL-4), a joint venture of EBMT, EORTC, ICHS, ELN and ESGICH/ESCMID.
J Infect. 2013 Dec 24. [Epub ahead of print]
Fourth European Conference on Infections in Leukaemia(ECIL-4): guidelines for diagnosis, prevention, and treatment of invasive fungal diseases in paediatric patients with cancer or allogeneic haemopoietic stem-cell transplantation.
Groll AH, Castagnola E, Cesaro S, Dalle JH, Engelhard D, Hope W, Roilides E, Jan Styczynski, Adilia Warris, and Lehrnbecher T.
Lancet Oncol 2014; 15: e327–40.
The Lancet Oncology
Discontinuation of empirical antibiotic therapy in neutropenic leukaemia patients with fever of unknown origin is ethical.
Orasch C, Averbuch D, Mikulska M, Cordonnier C, Livermore DM, Gyssens IC, Klyasova G, Engelhard D, Kern W, Viscoli C, Akova M, Marchetti O; for the 4th European Conference on Infections in Leukemia.
Clin Microbiol Infect 2015; 21: e25–e27
Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients. C Cordonnier, S Cesaro, G Maschmeyer, H Einsele, J P Donnelly, A Alanio, P M. Hauser, K Lagrou, W J G Melchers, J Helweg-Larsen, O Matos, S Bretagne and J Maertens. Journal of Antimicrobial Chemotherapy 2016, doi:10.1093/jac/dkw155.
ECIL guidelines for preventing Pneumocystis jirovecii pneumonia in patients with hematological malignancies and stem cell transplant recipients J Maertens, S Cesaro, G Maschmeyer, H Einsele, J P Donnelly, A Alanio, P M. Hauser, K Lagrou, W J G Melchers, J Helweg-Larsen, O Matos, S Bretagne and C Cordonnier Journal of Antimicrobial Chemotherapy 2016, doi:10.1093/jac/dkw157
ECIL guidelines for the diagnosis of Pneumocystis jirovecii pneumonia in patients with hematological malignancies and stem cell transplant recipients A Alanio, P M. Hauser, K Lagrou, W J G Melchers, J Helweg-Larsen, O Matos, S Cesaro, G Maschmeyer, H Einsele, J P Donnelly, C Cordonnier, J Maertens, S Bretagne Journal of Antimicrobial Chemotherapy 2016, doi:10.1093/jac/dkw156 Download
Response to “Comment on Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients ”by S. Antinori and colleagues.
C CORDONNIER, A ALANIO, S CESARO, G MASCHMEYER, H EINSELE, J. P DONNELLY, P M. HAUSER, K LAGROU, W J. G. MELCHERS, J HELWEG-LARSEN, O MATOS, S BRETAGNE, J MAERTENS on behalf of the 5th European Conference on Infections in Leukemia.
J. Antimicrob. Chemother. 2017 Jan 25. pii: dkw580. doi: 10.1093/jac/dkw580. [Epub ahead of print]
Management of viral hepatitis in patients with haematological malignancy and in patients undergoing haematopoietic stem cell transplantation: recommendations of the 5th European Conference on Infections in Leukemia.
V MALLET, F VAN BÖMMEL, C DOERIG, S PISCHKE, O HERMINE, A LOCASCIULLI, C CORDONNIER, T BERG, D MORADPOUR, H WEDEMEYER, P LJUNGMAN, on behalf of ECIL 5, a joint venture of EBMT, EORTC, ICHS and ELN.
Lancet Infectious Diseases 2016, 16 : 606-17
ECIL guidelines for the prevention, diagnosis and treatment of BK polyomavirus-associated haemorrhagic cystitis in haematopoietic stem cell transplant recipients
Simone Cesaro, Tina Dalianis, Christine Hanssen Rinaldo, Minna Koskenvuo, Anna Pegoraro, Hermann Einsele, Catherine Cordonnier and Hans H. Hirsch
J Antimicrob Chemother 2017, doi:10.1093/jac/dkx324
ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients.
Frederic Tissot, Samir Agrawal, Livio Pagano, Georgios Petrikkos, Andreas H. Groll, Anna Skiada, Cornelia Lass-Flörl, Thierry Calandra, Claudio Viscoli, Raoul Herbrecht. Haematologica 2017 : 102(3):433-444
Management of Epstein-Barr Virus infections and post-transplant lymphoproliferative disorders in patients after allogeneic hematopoietic stem cell transplantation: Sixth European Conference on Infections in Leukemia (ECIL-6) guidelines. J Styczynski, W van der Velden, C P. Fox, D Engelhard, R de la Camara, C Cordonnier, P Ljungman on behalf of the Sixth European Conference on Infections in Leukemia, a joint venture of the Infectious Diseases Working Party of the European Society of Blood and Marrow Transplantation (EBMT-IDWP), the Infectious Diseases Group of the European Organization for Research and Treatment of Cancer (EORTC-IDG), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN) Haematologica 2016 101(7):803-811
download
ECIL guidelines for treatment of Pneumocystis jirovecii pneumonia in non–HIV infected patients G Maschmeyer, J Helweg-Larsen, L Pagano, C Robin, C Cordonnier, P Schellongowski Journal of Antimicrobial Chemotherapy 2016, doi:10.1093/jac/dkw155
Vaccination of non-transplanted patients with haematological malignancies: Guidelines from the 2017 European Conference on Infections in Leukaemia (ECIL 7)
M MIKULSKA, S CESARO, H DE LA VALLADE, R DI BLASI, S EINARSDOTTIR, G GALLO, C RIEGER, D ENGELHARD, T LEHRNBECHER, P LJUNGMAN, C CORDONNIER
Lancet Infectious Diseases 2019, doi: 10.1016/s1473-3099(18)30601-7
Vaccination of Haematopoietic Stem Cell Transplant Recipients: Guidelines of the 2017 European Conference on Infections in Leukaemia (ECIL 7)
C CORDONNIER, S EINARSDOTTIR, S CESARO, R DI BLASI, M MIKULSKA, C RIEGER, H DE LA VALLADE, G GALLO, T LEHRNBECHER, D ENGELHARD, P LJUNGMAN
Lancet Infectious Diseases 2019, doi: 10.1016/s1473-3099(18)30600-5
Guidelines from the 2017 European Conference on Infections in Leukemia for management of HHV-6 infection in patients with hematological malignancies and after hematopoietic stem cell transplantation.
Ward KN, Hill JA, Hubacek P, de la Camara R, Crocchiolo R, Einsele H, Navarro D, Robin C, Cordonnier C, Ljungman P.
Haematologica. 2019 Aug 29. pii: haematol.2019.223073. doi: 10.3324/haematol.2019.223073
ECIL guidelines for the management of cytomegalovirus infection in patients with haematological malignancies and after stem cell transplantation
Per Ljungman, Rafael de la Camara, Christine Robin, Roberto Crocchiolo, Hermann Einsele, Joshua A Hill, Petr Hubacek, David Navarro, Catherine Cordonnier, Katherine N Ward on behalf of the 2017 European Conference on Infections in Leukaemia group
Lancet Infectious Diseases 2019, août;19(8):e260-e272. doi: 10.1016/S1473-3099(19)30107-0
Fluoroquinolone prophylaxis in haematological cancer patients with neutropenia: ECIL critical appraisal of previous guidelines.
Mikulska M, Averbuch D, Tissot F, Cordonnier C, Akova M, Calandra T, Ceppi M, Bruzzi P, Viscoli C; European Conference on Infections in Leukemia (ECIL).
J Infect. 2018 Jan;76(1):20-37. doi: 10.1016/j.jinf.2017.10.009. Epub 2017 Oct 25
ECIL guidelines on Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology
Georg Maschmeyer, Julien De Greef, Sibylle C. Mellinghoff, Annamaria Nosari, Anne Thiebaut-Bertrand, Anne Bergeron, Tomas Franquet, Nicole M. A. Blijlevens, Johan A. Maertens (on behalf of the European Conference on Infections in Leukemia (ECIL))
Received: 19 October 2018 / Revised: 31 December 2018 / Accepted: 11 January 2019
© The Author(s) 2019. This article is published with open access
Lehrnbecher T, Averbuch D, Castagnola E, Cesaro S, Ammann RA, Garcia-Vidal C, Kanerva J, Lanternier F, Mesini A, Mikulska M, Pana D, Ritz N, Slavin M, Styczynski J, Warris A, Groll AH; 8th European Conference on Infections in Leukaemia. 8th European Conference on Infections in Leukaemia: 2020 guidelines for the use of antibiotics in paediatric patients with cancer or post- haematopoietic cell transplantation. Lancet Oncol. 2021 Jun;22(6):e270-e280. doi: 10.1016/S1470-2045(20)30725-7.
Groll AH, Pana D, Lanternier F, Mesini A, Ammann RA, Averbuch D, Castagnola E, Cesaro S, Engelhard D, Garcia-Vidal C, Kanerva J, Ritz N, Roilides E, Styczynski J, Warris A, Lehrnbecher T; 8th European Conference on Infections in Leukaemia. 8th European Conference on Infections in Leukaemia: 2020 guidelines for the diagnosis, prevention, and treatment of invasive fungal diseases in paediatric patients with cancer or post-haematopoietic cell transplantation. Lancet Oncol. 2021 Jun;22(6):e254-e269. doi: 10.1016/S1470-2045(20)30723-3.